Tīmeklis1998. gada 2. marts · The identity of RhoA codon 40 is critically important for RhoA-mediated SRF activation: mutant E40L was inactive in both assays, while E40W was inactive in transfection assays but weakly active in the microinjection assay. (The failure of some effector-loop mutants to score as defective in the microinjection assay … TīmeklisRhoA is a small GTPase that regulates many functions, such as motility and phenotypic regulation of smooth muscle cells. RhoA is dependent upon a stimulus, and it can drive the contractile ... (SRF) - myocardin signaling axis is a major determinant of SMC differentiation. Under normal healthy conditions, myocardin and myocardin-related ...
RhoA Signaling via Serum Response Factor Plays an …
Tīmeklis2014. gada 1. sept. · RhoA modulates the activity of SRF, NF-kappaB, c/EBPb, Stat3, Stat5, FHL-2, PAX6, GATA-4, E2F, estrogen receptor alpha, estrogen receptor beta, CREB, and transcription factors that depend on the JNK and p38 MAP kinase pathways. Substrates to these kinases include c-Jun, ELK, PEA3, ATF2, MEF2A, Max and … TīmeklisIzstāde Skola 2024. No 3 līdz 5 martam Rīgas Aeronavigācijas institūts (RAI) ņēma dalību nozīmīgākajā izglītības iespēju notikumā Latvijā izstādē ”Skola 2024”. … stanford university sweatshirts on sale
SRF and SRF-binding proteins regulate SIRT2 gene ... - ResearchGate
Tīmeklis2024. gada 2. jūl. · Levels of RhoA, rho-associated protein kinase-2 (ROCK2), myocardin-related transcription factor-A (MRTF-A), serum response factor (SRF), … Tīmeklis2024. gada 1. okt. · RhoA acts as a molecular switch due to its GTPase activity, which cycles RhoA between an active GTP-bound state and an inactive GDP-bound state ( … TīmeklisRhoA also stimulates the autoregulatable murine SRF promoter in myoblasts, and the expression level of SRF is reduced in myoblasts overexpressing N19-RhoA. This … stanford university swimming team