Flotillin complex

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August undefined, 2024

WebWikipedia WebAutoantibodies might interfere with the flotillin 1/2 complex and counteract axonal integrity due to the function of flotillin proteins in axon growth (10, 11). Anti-flotillin-1/2 complex autoantibodies were identified in patients with multiple sclerosis ( 12 ), but until now, not in patients with severe cognitive impairment.

Flotillin-1 Interacts With and Sustains the Surface Levels of TRPV2 ...

WebTwo flotillin members have been described, flotillin-1 and flotillin-2. In addition to its colocalization with lipid rafts on the plasma membrane, flotillin-1 also has been found in compartments of the endocytic and autophagosomal pathways, such as recycling/late endosomes, the Golgi complex, and the nucleus (6,7). WebTranscripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. diabetic friendly almond cake

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• Schroeder WT, Stewart-Galetka S, Mandavilli S, et al. (1994). "Cloning and characterization of a novel epidermal cell surface antigen (ESA)". J. Biol. Chem. 269 (31): 19983–91. doi:10.1016/S0021-9258(17)32117-8. PMID 8051082. • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. WebSep 18, 2012 · We recently identified flotillin-1 as a key regulator of EGF receptor and the downstream mitogen activated protein kinase (MAPK) ERK1/2 signaling. In this cascade, flotillin-1 forms a molecular complex … WebNational Center for Biotechnology Information diabetic friendly appetizers

Flotillin-1/reggie-2 protein plays dual role in activation of receptor ...

Flotillin-1 Antibody (C-2) SCBT - Santa Cruz Biotechnology

WebExtensive quantitative proteomic analysis allowing comparison of the isolated populations showed that several classically used exosome markers, like major histocompatibility complex, flotillin, and heat-shock 70-kDa proteins, are similarly present in all EVs. WebJul 20, 2024 · To the best of our knowledge, this is the first report showing molecular details underlying formation of the MPP1-flotillin complex that opens a new outlook in our … diabetic friendly atta in usaWebJul 14, 2024 · Loss of flotillins leads to a decrease in membrane fluidity that in turn leads to alterations in MreB dynamics and, as a consequence, in peptidoglycan synthesis. These alterations are reverted when membrane fluidity is restored by a chemical fluidizer. In vitro, the addition of a flotillin increases membrane fluidity of liposomes. diabetic friendly apple pie

"WebSep 18, 2012 · We recently identified flotillin-1 as a key regulator of EGF receptor and the downstream mitogen activated protein kinase (MAPK) ERK1/2 signaling. In this cascade, … " - Flotillin complex

Flotillin complex

Anaplasma phagocytophilum Hijacks Flotillin and NPC1 …

WebApr 5, 2024 · Immunoglobulin G subclasses of anti-flotillin-1/2 antibodies were predominantly 1 and 3. We confirm that antibodies targeting the flotillin-1/2 complex are present in a subgroup of patients with ... WebOct 26, 2024 · Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe …

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WebJun 23, 2024 · Flotillin-1 and Flotillin-2 (synonyms: reggie-2 and reggie-1) were originally described to be upregulated in regenerating axons of goldfish retinal ganglion cells after … http://amigo.geneontology.org/amigo/term/GO:0016600#:~:text=A%20protein%20complex%20that%20contains%20flotillin-1%20and%20flotillin-2%2C,proteins.%20Flotillins%20associate%20into%20membrane%20microdomains%20resembling%20caveolae.

WebWestern blot was performed using Anti- Flotillin 1 Polyclonal Antibody ( Product # PA5-19713) and a 47kDa band corresponding to Flotillin 1 was observed across all the cell … WebPart of flotillin complex. Is active in glutamatergic synapse and presynaptic active zone membrane. Orthologous to human FLOT2 (flotillin 2); PARTICIPATES IN insulin signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8 …

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WebJul 3, 2024 · Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are associated with obesity. They are accompanied by increased levels of free cholesterol in the liver. Most free cholesterol resides within the plasma membrane. We assessed the impact of adding or removing free cholesterol on the function and …

WebFeb 9, 2024 · Using site-specific mapping, we also uncovered that the SPFH (stomatin, prohibitin, flotillin, and HflK/C) domain of flotillin-1 interacted with TRPV2 N-termini and transmembrane domains 1-4, respectively. Our findings therefore demonstrate that flotillin-1 is a key element in TRPV2 signaling complex and modulates its cellular response. diabetic friendly baked french toastWebERLIN2, also named as C8orf2 and SPFH2, is a component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1, 4, 5-trisphosphate receptors (IP3Rs) such as ITPR1. It promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin … diabetic friendly bakeries njWebDec 1, 2011 · Flotillins have been implicated in myriad processes that include endocytosis, signal transduction and regulation of the cortical cytoskeleton, yet the molecular … diabetic friendly bakeryWebMay 28, 2024 · We then treated the cells with the cross-linker DSP and immunoprecipitated flotillin-1 with Flag antibody. Similar amounts of Flag signal and flotillin-2 were … cindy studerWebDec 15, 2014 · ABSTRACT. Flotillin 1 and 2 are ubiquitous and highly conserved proteins. They were initially discovered in 1997 as being associated with specific caveolin-independent cholesterol- and glycosphingolipid-enriched membrane microdomains and as being expressed during axon regeneration. Flotillins have a role in a large number of … diabetic friendly bakeries charlotte ncWebOct 20, 2024 · d, e Interaction networks of the V-ATPase (d) and the flotillin (e) complex. f Co-IP of ATP6V1D and FZD9 (n = 2). ATP6V1B2 and ATP6V1A1 are known members of the V-ATPase complex; LAMP2 is a ... diabetic friendly bakeries near meWebIn addition, co-immunoprecipitation experiments revealed that flotillins 1 and 2 are part of a stable hetero-oligomeric complex that contains both caveolins 1 and 2. However, protein levels of flotillin-1 and flotillin-2/ESA remain unchanged in response to oncogenic transformation of NIH 3T3 cells. diabetic friendly asian food